The Orlando Sentinel is reporting that WDW will be closed all day Friday, October 7 due to the hurricane. Closing WDW is fairly rare, the last time probably being on 9/11. Predictions of high winds and heavy rain prompted the closing.
Disney Cruise Line, as well as other lines, are obviously being affected. Cruises to the Bahamas are being cancelled, and other cruises leaving from Port Canaveral in the near term will depend on the condition of the port. This hurricane might do an unusual loop back around, according to some of the models, and possibly stall out offshore. This would at least make for some rough sailing or possibly disruption to cruise line itineraries.